COMPOSITIONS AND METHODS FOR INHIBITION OF ALPHAVIRUS INFECTION

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United States of America Patent

APP PUB NO 20240124553A1
SERIAL NO

18472918

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure is directed to compositions and methods of treating arthritogenic alphavirus infection. Compositions include a fusion protein comprising an Fc region, a first Mxra8 region, and a second Mxra8 region, wherein the fusion protein reduces inflammation and infection by an arthritogenic alphavirus. Methods include administering the fusion protein to a mammalian or non-mammalian subject to reduce or inhibit alphavirus infection.

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Patent Owner(s)

Patent OwnerAddress
WASHINGTON UNIVERSITYONE BROOKINGS DRIVE ST LOUIS MO 63130

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Basore, Katherine St. Louis, US 3 0
Diamond, Michael St. Louis, US 25 99
Fremont, Daved St. Louis, US 14 42
Kim, Arthur St. Louis, US 3 0
Nelson, Christopher A St. Louis, US 15 214
Raju, Saravanan St. Louis, US 2 0
Thackray, Larissa St. Louis, US 5 9
Zhang, Rong St. Louis, US 207 1676
Zimmerman, Maxwell St. Louis, US 1 0
Zimmerman, Ofer St. Louis, US 17 645

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