METHODS AND SYSTEMS FOR MEASURING ENDOGENOUS ANALYTES UTILZING AN ORIGIN-ADJUSTED APPROACH
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United States of America Patent
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Issued Date -
Apr 11, 2024
app pub date -
Oct 10, 2023
filing date -
Oct 11, 2022
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Abstract
The field of biomarker detection and drug development is constantly in pursuit of more accurate, reliable, rapid, and inexpensive technology. Methods and systems for quantifying an analyte of interest disclosed herein include steps of obtaining a sample, spiking the sample with the analyte of interest, separating and detecting the sample using LC-MS, and calculating a linear regression of a sample using analytical techniques are described herein. Further, these methods and systems preclude the use and/or calculation of endogenous amounts of analyte present in a sample, yielding to methods and systems that provide increased speed and accuracy for measuring sample analytes.
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