T cell receptors and fusion proteins thereof

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 12065475
APP PUB NO 20240109950A1
SERIAL NO

18542441

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Abstract

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The present disclosure provides T cell receptor (TCR) fusion proteins comprising a TCR that binds to a GVYDGREHTV (SEQ ID NO:34) HLA-A*02 complex that is covalently linked to a T cell engaging domain that binds a protein expressed on a cell surface of a T cell and an antibody Fc domain, as well as polynucleotides, vectors, kits, host cells, pharmaceutical compositions, methods, and uses related thereto.

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Patent Owner(s)

Patent OwnerAddress
IMMUNOCORE LTDABINGDON

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Conroy, Paul Abingdon, GB 10 28
Hearty, Stephen Abingdon, GB 3 6
Mak, Lok Hang Abingdon, GB 3 6

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