Fluorescence Detection of Circulating Cell Free DNA Including Within Extracellular Vesicles in Biospecimens and Liquid Biopsies
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United States of America Patent
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Issued Date -
Mar 28, 2024
app pub date -
Sep 15, 2023
filing date -
Mar 15, 2021
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Abstract
The present invention relates in general to the field of rapid detection and quantification of tissue/organ injury, and more particularly, to a novel platform for monitoring and quantification of circulating cell-free DNA including within extracellular vesicles, together with extracellular vesicles specific markers, and extracellular vesicles sizes also in combination with PCR-related technologies in biospecimens, and liquid biopsies for the assessment and prediction of severity of tissue/organ injury, monitoring of disease progression as well as the assessment of the response to therapeutic interventions.
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