D-amino acid oxidase mutants and uses thereof in preparing L-glufosinate

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United States of America Patent

PATENT NO 12060584
APP PUB NO 20240101974A1
SERIAL NO

18469527

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Abstract

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Embodiments of the present disclosure relate to a D-amino acid oxidase mutant and application in preparing L-glufosinate thereof. The D-amino acid oxidase mutant has an amino acid substitution at at least one of position 62 and position 226 of an amino acid sequence of the D-amino acid oxidase mutant when compared to an amino acid sequence of a D-amino acid oxidase as set forth in SEQ ID NO. 1, the position 62 and position 226 being defined with reference to SEQ ID NO. 1, and the amino acid sequence of the D-amino acid oxidase mutant having at least 90% identity to SEQ ID NO. 1.

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Patent OwnerAddress
EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGYSHANGHAI

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Liu, Qinghai Shanghai, CN 2 1
Luo, Zhonghua Yinchuan, CN 10 6
Wang, Hualei Shanghai, CN 55 64
Wei, Dongzhi Shanghai, CN 3 0
Wu, Chengjun Shaoxing, CN 8 3
Zhang, Changlei Shaoxing, CN 1 0
Zhang, Jian Shanghai, CN 1504 17611

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