INHIBITORS OF SHORT-CHAIN DEHYDROGENASE ACTIVITY FOR PROMOTING NEUROGENESIS AND INHIBITING NERVE CELL DEATH

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United States of America Patent

APP PUB NO 20240100026A1
SERIAL NO

18196106

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Abstract

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A method of promoting neuroprotection in a subject from axonal degeneration, neuronal cell death, and/or glia cell damage after injury, augmenting neuronal signaling underlying learning and memory, stimulating neuronal regeneration after injury, and/or treating a disease, disorder, and/or condition of the nervous system in a subject in need thereof includes administering to the subject a therapeutically effective amount of a 15-PGDH inhibitor.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF IOWA RESEARCH FOUNDATION112 N CAPITOL STREET 6 GILMORE HALL IOWA CITY IA 52242-5500
THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS810 VERMONT AVENUE N W WASHINGTON DC 20420

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
MARKOWITZ, Sanford Pepper Pike, US 52 148
PIEPER, Andrew Shaker Heights, US 5 43
READY, Joseph Carrollton, US 31 97

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