NOVEL PRMT5 INHIBITORS
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United States of America Patent
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Issued Date -
Mar 21, 2024
app pub date -
Nov 6, 2023
filing date -
Dec 16, 2020
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Abstract
Described herein are novel PRMT5 inhibitors of Formula I and pharmaceutically acceptable salts thereof, as well as the pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity and may have use in treating proliferative, metabolic and blood disorders. Compounds of Formula I have the following structure:
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