METHODS FOR ANALYZING NUCLEIC ACIDS
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United States of America Patent
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Issued Date -
Mar 7, 2024
app pub date -
Feb 9, 2023
filing date -
Jul 30, 2020
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Abstract
Provided herein are methods, systems, and compositions for determining a base in a polynucleotide. In various aspects, the methods, systems, and compositions presented herein are useful for performing 4-base, 5-base, or 6-base sequencing of polynucleotide molecules, for example, from liquid biopsy samples or wherein the base is a low frequency mutation.
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