DATABASE FOR THERAPEUTIC INTERVENTIONS
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United States of America Patent
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Issued Date -
Feb 29, 2024
app pub date -
Aug 24, 2022
filing date -
Aug 24, 2022
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Abstract
This disclosure provides, among other things, methods for compiling and using a database for identifying one or more therapeutic interventions for a cancer and/or the efficacy of a therapeutic intervention for subjects with a tumor genomic profile. The database may include, for each of a plurality of subjects having cancer: (i) tumor genomic testing data, including somatic alterations, collected at two or more time intervals per subject via serial biopsy of cell-free DNA, (ii) one or more therapeutic interventions administered to each of the subjects at one or more times; and (iii) efficacy of the therapeutic interventions.
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