BIOMARKER FOR PREDICTING AGE IN DAYS OF PIGS, AND PREDICTION METHOD
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United States of America Patent
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Issued Date -
Feb 29, 2024
app pub date -
Nov 6, 2023
filing date -
Jul 31, 2020
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Abstract
Disclosed are biomarkers and a prediction method for predicting age in days in pigs. The biomarkers for predicting age in days of pigs include one or more CpG sites with different methylation levels, and the different methylation levels of the CpG sites correspond to different ages in days of pigs. An Elastic Net linear regression model is constructed by using the methylation levels of the CpG sites and the weights corresponding to each CpG site, thereby predicting age in days of pigs to be tested. The above prediction method has high accuracy, and is accurate and reliable in detecting age in days of pigs, which fills the gap in the age prediction model of pigs based on DNA methylation, and provides an ideal model for investigating important scientific issues such as development and aging of human and animals.
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