DELIVERY OF ABETA VARIANTS FOR AGGREGATION INHIBITION
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United States of America Patent
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Feb 15, 2024
app pub date -
Dec 15, 2021
filing date -
Dec 18, 2020
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Aspects of the present disclosure are directed to compositions and methods for treating a subject having a neurodegenerative disorder, disease, or condition. Certain aspects relate to treatment with a therapeutically effective amount of a composition comprising a vector encoding an Aβ peptide variant. Further aspects relate to methods of inhibiting aggregation of endogenous Aβ peptide in vivo by contacting at least one such peptide with a therapeutically effective amount of an expressed Aβ peptide variant from a vector encoding the Aβ peptide variant, said vector in a composition.
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