MUTANT L-PIPECOLIC ACID HYDROXYLASE AND CIS-5-HYDROXY-L-PIPECOLIC ACID PRODUCTION METHOD UTILIZING SAME
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Feb 8, 2024
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Dec 24, 2021
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Dec 25, 2020
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The present invention aims to provide a mutant L-pipecolic acid hydroxylase for highly productive and highly selective production of cis-5-hydroxy-L-pipecolic acid by hydroxylation of L-pipecolic acid, and to provide a novel method for industrially producing cis-5-hydroxy-L-pipecolic acid from L-pipecolic acid with high productivity at low cost. The present invention provides a mutant L-pipecolic acid hydroxylase having an amino acid sequence that a particular amino acid mutation(s) is/are introduced in the amino acid sequence of SEQ ID NO:2.
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