COMPOSITIONS COMPRISING IDURONATE-2-SULFATASE

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United States of America Patent

APP PUB NO 20240043817A1
SERIAL NO

18052442

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides, among other things, improved methods for purifying I2S protein produced recombinantly for enzyme replacement therapy. The present invention is, in part, based on the surprising discovery that recombinant I2S protein can be purified from unprocessed biological materials, such as, I2S-containing cell culture medium, using a process involving as few as four chromatography columns.

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Patent Owner(s)

Patent OwnerAddress
TAKEDA PHARMACEUTICAL COMPANY LIMITED1-1 DOSHOMACHI 4-CHOME CHUO-KU OSAKA-SHI OSAKA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Nichols, Dave Lexington, US 17 36

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