Methods for Producing Fabs and IgG Bispecific Antibodies
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United States of America Patent
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Feb 8, 2024
app pub date -
Oct 10, 2023
filing date -
Dec 22, 2016
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Abstract
Methods for producing Fabs and IgG bi-specific antibodies comprising expressing nucleic acids encoding designed residues in the CH1/CL interface are provided. Also provided are Fabs and IgG bi-specific antibodies produced according to the provided methods as well as nucleic acids, vectors and host cells encoding the same.
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