CYTOCHROME P450 ENZYME MUTANT AND APPLICATION THEREOF
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United States of America Patent
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Jan 11, 2024
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Apr 25, 2021
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Jan 13, 2021
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Provided are a cytochrome P450 enzyme mutant and an application thereof. The enzyme activity and anti-Markov oxidation selectivity of P450 derived from a wild-type strain of Bacillus megaterium undergo protein modification by means of directed evolution, thus improving enzyme activity and selectivity, and developing a series of P450 enzyme mutants that may be used for industrial production.
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