NOVEL VHL SMALL MOLECULE PROBES
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United States of America Patent
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Issued Date -
Jan 4, 2024
app pub date -
Nov 8, 2021
filing date -
Nov 9, 2020
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Abstract
The present disclosure relates to compositions and methods for use in modulating von Hippel-Lindau protein (pVHL) and in identifying pVHL ligands, which can be useful in, for example, treating anti-chronic anemia and anti-chronic ischemia, and also as proteolysis targeting chimeras (PROTACS) to degrade proteins for various therapeutic applications. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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