SMALL MOLECULE INHIBITORS OF NF-kB INDUCING KINASE
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United States of America Patent
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Issued Date -
Dec 28, 2023
app pub date -
Nov 11, 2021
filing date -
Nov 11, 2021
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Abstract
This invention relates to compounds of Formula I that inhibit NIK and pharmaceutical compositions comprising such compounds and methods of using the same. These compounds and pharmaceutical compositions are useful for preventing or treating diseases such as cancer (such as B-cell malignancies including leukemias, lymphomas and myeloma), inflammatory disorders, autoimmune disorders, immunodermatologic disorders such as palmoplantar pustulosis and hidradenitis suppurativa, and metabolic disorders such as obesity and diabetes.
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