HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE
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United States of America Patent
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Dec 21, 2023
app pub date -
Oct 26, 2021
filing date -
Oct 27, 2020
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Abstract
The present disclosure provides compounds of Formula (I) having activity as inhibitors of G12C mutant KRAS protein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses and methods of treating certain disorders, such as cancer, including but not limited to lung, pancreatic and colorectal cancers.
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