SPECIFIC ANTIBODY-DRUG-CONJUGATES (ADCS) WITH KSP INHIBITORS AND ANTI-CD123-ANTIBODIES

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United States of America Patent

APP PUB NO 20230399411A1
SERIAL NO

18336769

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Abstract

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The invention relates to specific Antibody-Drug-Conjugates (ADCs) with KSP inhibitors and anti-CD123-antibodies, to the use of these conjugates for the treatment and/or prophylaxis of diseases and to the use of these conjugates for preparing medicaments for treatment and/or prevention of diseases, in particular hyperproliferative and/or angiogenic disorders such as, for example, cancer diseases. Such treatments can be carried out as monotherapy or else in combination with other medicaments or further therapeutic measures.

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Patent Owner(s)

Patent OwnerAddress
BAYER PHARMA AKTIENGESELLSCHAFT178 13353 MUELLERSTRASSE BERLIN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CANCHO, GRANDE Yolanda Leverkusen, DE 56 247
GREVEN, Simone Dormagen, DE 47 414
KIRCHHOFF, Dennis Berlin, DE 16 72
LERCHEN, Hans-Georg Leverkusen, DE 88 616
MÄRSCH, Stephan Köln, DE 16 101
MAHLERT, Christoph Wuppertal, DE 34 280
REBSTOCK, Anne-Sophie Champagne au Mont d'Or, FR 52 212
STELTE-LUDWIG, Beatrix Wülfrath, DE 59 429
WITTROCK, Sven Berlin, DE 37 134

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