METHOD AND SYSTEM FOR EARLY EFFICIENT DETECTION OF CO-EVOLUTIONARY SITES IN EVOLVING BIO-NETWORKS
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United States of America Patent
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Dec 7, 2023
app pub date -
Sep 30, 2021
filing date -
Sep 30, 2020
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Abstract
A method and system are disclosed for efficient early detection of co-evolutionary sites among genomic sequences. Exemplary embodiments extract/approximate a data motif complex of a given data set wherein the extraction procedure can be performed using at least two steps. One step is construction of a vertex set of the data motif complex by identifying data sites with high informational variation. Another step is construction of higher dimensional simplices which systematically represent informational patterns within the data set. The method and system can be implemented as a computer-implemented software pipeline as described herein. An exemplary application can rapidly recognize key or critical mutational blocks in viral SARS-CoV-2 genomic data.
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