COOLING ELEMENT, SHIPPING BOX WITH A COOLING ELEMENT, METHOD FOR TEMPERATURE STABILISATION, AND USE OF A COOLING ELEMENT
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United States of America Patent
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Issued Date -
Dec 7, 2023
app pub date -
Oct 19, 2021
filing date -
Oct 20, 2020
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Abstract
A cooling element includes a container, the container defining an internal volume within one or more walls of the container. The volume is air-tight sealed, and the container is configured for containing dry ice (solid carbon dioxide), releasing carbon dioxide gas from the volume and blocking ingress of ambient gas into the volume. Additionally, a shipping box includes a thermally insulated volume therein, and is configured for holding a receptacle and one or more cooling elements, wherein the one or more cooling elements are arranged to enclose the receptacle. Further, a method is disclosed for thermal stabilisation of such a receptacle by using the cooling element or shipping box. The receptacle is arranged for holding a product such as a (bio)pharmaceutical substance and/or advanced therapy medicinal product(s).
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