MODIFIED HEXOSAMINIDASE AND USES THEREOF

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United States of America Patent

APP PUB NO 20230374483A1
SERIAL NO

18004605

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Abstract

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The disclosure provides for vectors encoding a fusion polypeptide comprising a modified hexosaminidase beta-subunit that forms homodimers, a linker and an ApoE peptide that allows for transport across the blood brain barrier, the encoded polypeptide, and methods of using the vector or polypeptide.

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Patent Owner(s)

Patent OwnerAddress
REGENTS OF THE UNIVERSITY OF MINNESOTA600 MCNAMARA ALUMNI CENTER 200 OAK STREET SE MINNEAPOLIS MN 55455-2020

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ou, Li Eden Prairie, US 21 3
Whitley, Chester B Brooklyn Park, US 9 47

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