MAdCAM-1 POLYPEPTIDES AND USES THEREOF
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United States of America Patent
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Issued Date -
Nov 9, 2023
app pub date -
Nov 17, 2022
filing date -
Dec 31, 2020
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Abstract
MAdCAM-1 polypeptides are provided. Accordingly there is provided a polypeptide comprising an amino acid sequence of MAdCAM-1 capable of binding alpha4beta7 integrin, wherein said polypeptide is in association with a therapeutic or a detectable moiety. Also provided are methods of treating and diagnosing inflammation mediated by MAdCAM-1.
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