INNATE IMMUNE PROTEINS AS BIOMARKERS FOR CNS INJURY

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United States of America Patent

APP PUB NO 20230349929A1
SERIAL NO

18347108

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides novel markers of the severity of a central nervous system injury, such as spinal cord injury or traumatic brain injury, in a patient. In particular, protein components of inflammasomes in the cerebrospinal fluid that can be used to assess the severity of central nervous system injury in a patient are disclosed. Methods of using such protein biomarkers to determine a prognosis, direct treatment and rehabilitation efforts, and monitor response to treatment for a patient with a central nervous system injury are also described.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF MIAMIOFFICE OF TECHNOLOGY TRANSFER 1951 NW 7TH AVENUE - 3RD FLOOR SUITE 310 MIAMI FL 33136

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
ADAMCZAK, Stephanie Miami, US 4 8
BULLOCK, M Ross Miami, US 5 17
DE, RIVERO VACCARI Juan Pablo Miami, US 15 29
DIETRICH, W Dalton Miami, US 21 44
KEANE, Robert W Miami, US 22 38
LEVI, Allan Miami, US 6 8
WANG, Michael Y Miami, US 11 24

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