IMIDAZOPYRIDAZINE AND IMIDAZOPYRAZINE COMPOUNDS AS INHIBITORS OF CDK7

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United States of America Patent

APP PUB NO 20230348475A1
SERIAL NO

18245715

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Compounds having activity as anti-cancer agents are provided. The compounds have the following structure (I) or a pharmaceutically acceptable salt, stereoisomer or tautomer, thereof, wherein X, Y, R1, R2, R3R4, R5 and L are as defined herein. This disclosure provides methods associated with preparation and use of such compounds, pharmaceutical compositions comprising such compounds, and methods for treating a CDK7-dependent disease (e.g., cancer).

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TRANSLATIONAL GENOMICS RES INSTNot Provided

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
DANA, Srikanta Phoenix, US 2 0
KAADIGE, Mohan Scottsdale, US 9 10
KASIBHATLA, Srinivas Rao San Diego, US 37 666
SHARMA, Sunil Phoenix, US 57 491
THODE, Trason Phoenix, US 9 2
WESTON, Alexis Phoenix, US 10 3

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