Heteroaryl Derivative, Preparation Method Therefor, And Use Thereof

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United States of America Patent

APP PUB NO 20230348467A1
SERIAL NO

17791283

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Abstract

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The present invention relates to heteroaryl derivatives, preparation methods therefor, and applications thereof in medicine. Specifically, the present invention relates to a heteroaryl derivative represented by general formula (AI), a preparation method therefor, and a pharmaceutically acceptable salt, and use thereof as a therapeutic agent, in particular, as an SHP2 allosteric inhibitor, wherein the definition of substituents in general formula (AI) is the same as that in the description.

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Patent Owner(s)

Patent OwnerAddress
SHANGHAI ARYL PHARMTECH CO LTDBUILDING 3 301 MINQIANG ROAD SONGJIANG DISTRICT SHANGHAI 201612

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bie, Pingyan Shanghai, CN 4 24
Cao, Hai Shanghai, CN 3 41
Cao, Qi Shanghai, CN 41 299
Chen, Lei Taizhou, CN 979 4055
Guo, Yanghui Shanghai, CN 10 0
Hu, Taishan Shanghai, CN 35 359
Huang, Xiangui Shanghai, CN 3 0
Li, Wenpeng Shanghai, CN 9 7
Liao, Weiwei Shanghai, CN 6 0
Meng, Lichen Shanghai, CN 5 0
Qiu, Zongxing Shanghai, CN 13 208
Shen, Weichao Shanghai, CN 1 0
Wang, Xin Shanghai, CN 1487 14353
Wu, Nuoyi Shanghai, CN 1 0
Xing, Qingna Shanghai, CN 1 0
Yan, Qingyan Shanghai, CN 3 0
Ye, Cheng Shanghai, CN 22 62

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