BRIDGED NUCLEOSIDE AND NUCLEOTIDE USING SAME

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United States of America Patent

APP PUB NO 20230340008A1
SERIAL NO

17791799

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed are a bridged nucleoside and a nucleotide using the same. The nucleoside of the present invention is represented by the formula (I) below. The bridged nucleoside of the present invention is usable as a substitute for a phosphorothioate-modified nucleic acid, which has a risk of, for example, accumulation in a specific organ. The bridged nucleoside also has excellent industrial productivity.

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Patent Owner(s)

Patent OwnerAddress
OSAKA UNIVERSITYOSAKA
JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF NATIONAL INSTITUTE OF HEALTH SCIENCES3-25-26 TONOMACHI KAWASAKI-KU KAWASAKI-SHI KANAGAWA 210-9501

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
INOUE, Takao Kawasaki-shi, Kanagawa, JP 204 3324
KOMINE, Hibiki Osaka, JP 1 0
OBIKA, Satoshi Osaka, JP 50 1737
SUGIURA, Takaya Osaka, JP 2 0
YAMAGUCHI, Takao Osaka, JP 197 4627
YOSHIDA, Tokuyuki Kawasaki-shi, Kanagawa, JP 6 3

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