METHOD FOR PREPARING ATELOCOLLAGEN PREPARED IN HIGH PURITY AND HIGH YIELD AND USE THEREOF
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United States of America Patent
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Oct 19, 2023
app pub date -
Sep 9, 2021
filing date -
Sep 10, 2020
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Abstract
Provided are a method of preparing atelocollagen and use thereof, more specifically, a method of removing immunogens from pig skin-derived collagen and preparing high-purity atelocollagen with high yield, and use thereof. Atelocollagen prepared with high yield, according to a preparation method of the present disclosure, has high purity, a low immune response, no cytotoxicity, excellent in vivo biodegradability, and high safety, and therefore, may be used in a form of a bio-ink capable of forming high-resolution structures with excellent morphological characteristics and division ability, and therefore, is expected to be used for the development of a product for tissue and regeneration engineering, including a cell scaffold capable of easily forming blood vessels and controlling drug delivery.
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