COMPOSITIONS AND METHODS OF RNA ANALYSIS
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United States of America Patent
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Issued Date -
Oct 12, 2023
app pub date -
Jun 14, 2023
filing date -
Jul 24, 2015
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Abstract
The present disclosure relates to compositions and methods of RNA analysis. In particular, the present disclosure provides a method of RNA analysis that includes obtaining a sample, applying one or more multi-partite probes to the sample, where each of the one or more multi-partite probes includes at least two sub-probes, annealing at least one of the applied one or more multi-partite probes to at least one target nucleic acid within the sample, and ligating the at least two sub-probes associated with the at least one annealed multi-partite probe to create a target nucleic acid proxy that can be detected.
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