DIET CONTROLLED EXPRESSION OF A NUCLEIC ACID ENCODING CAS9 NUCLEASE AND USES THEREOF

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United States of America Patent

APP PUB NO 20230313161A1
SERIAL NO

18153490

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Abstract

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The present invention relates to a nucleic acid for the controlled expression of a nucleic acid encoding a Cas nuclease in an individual, comprising (i) a regulatory polynucleotide comprising a minimal promoter and from one to twenty AARE nucleic acids, and (ii) a nucleic acid encoding a Cas nuclease, which is placed under the control of the regulatory polynucleotide,

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Patent Owner(s)

Patent OwnerAddress
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)3 RUE MICHEL ANGE PARIS 75016
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS55 BOULEVARD DIDEROT PARIS 75012
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)PARIS FRA PARIS PARIS
COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (CEA)15 RUE LEBLANC PARIS 75015
SORBONNE UNIVERSITE21 RUE DE L'ECOLE DE MEDECINE PARIS 75006
IMC (INSTITUT DU CERVEAU DET DE LA MOELLE EPINIERE)HOPITAL PITIE SALPETRIERE 47/83 BOULEVARD DE L'HOPITAL PARIS 75013

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
MALLET, Jacques Paris, FR 41 255
RAVASSARD, Philippe Paris, FR 8 5
SERGUERA, Ché Paris, FR 2 0

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