METHOD FOR PREPARING T CELLS FOR ADOPTIVE T CELL THERAPY

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United States of America Patent

APP PUB NO 20230313140A1
SERIAL NO

17712787

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Abstract

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Disclosed is a method for preparing T cells for adoptive T cell therapy by contacting a population of activated T cells with an Eukaryotic initiation factor-4A (eIF4A) inhibitor. Also disclosed is a kit, a population of T cells or engineered T cells produced by the method and use of the same in adoptive T cell therapy and the treatment of cancer.

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Patent Owner(s)

Patent OwnerAddress
ST JUDE CHILDREN'S RESEARCH HOSPITAL INCMAIL STOP 742 262 DANNY THOMAS PLACE MEMPHIS TN 38105-3678

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
GREEN, Douglas R Memphis, US 35 396
GUO, Ao Memphis, US 19 11
LIEDMANN, Swantje Memphis, US 1 0

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