BINDING MOLECULES AGAINST BCMA AND USES THEREOF

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United States of America Patent

APP PUB NO 20230295322A1
SERIAL NO

17934064

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure provides BCMA binding molecules that specifically bind to human BCMA, conjugates comprising the BCMA binding molecules, and pharmaceutical compositions comprising the BCMA binding molecules and the conjugates. The disclosure further provides methods of using the BCMA binding molecules to treat cancers that express cell surface BCMA. The disclosure yet further provides recombinant host cells engineered to express the BCMA binding molecules and methods of producing the BCMA binding molecules by culturing the host cells under conditions in which the BCMA binding molecules are expressed.

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Patent Owner(s)

Patent OwnerAddress
NOVARTIS AGBASEL SUI

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
ABUJOUB, Aida Winchester, US 14 85
BLANKENSHIP, John Acton, US 21 223
FLEMING, Tony Stow, US 17 182
HOLMBERG, Brian Somerville, US 12 57
HONG, Connie Somerville, US 14 67
HUANG, Lu Cambridge, US 80 417
LU, Haihui Cambridge, US 40 483

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