Method and compounds for inhibiting the MCM complex and their application in cancer treatment
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United States of America Patent
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Issued Date -
Sep 21, 2023
app pub date -
Apr 17, 2023
filing date -
May 9, 2012
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A method for treating cancer by using an agent which is capable of inhibiting the functionality of the MCM complex, a heterohexameric ring formed from six subunits, in the process of DNA replication and a method of screening for such agents by detecting the locations and functions of the MCM subunits, such as hMcm2 and hMcm6, in cells treated with candidate compounds.
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