DIGITAL MICROFLUIDICS MULTI-DYNAMIC RANGE PARALLEL BIOCHEMICAL ASSAYS
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United States of America Patent
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Sep 14, 2023
app pub date -
Oct 10, 2022
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Oct 10, 2022
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Abstract
The invention relates generally to biochemical assays and more particularly to digital microfluidics multi-dynamic range parallel biochemical assays. The invention provides methods that enable improved precision and linearity for digital microfluidics analyses (i.e., analyses performed on a droplet actuator using droplet operations), including for example, assays related to measuring analytes in a biological sample. Examples of assays that may be performed using a method of the invention include measuring analytes in blood, including analytes from blood components, such as analytes present in plasma. The invention provides a digital microfluidics device (or cartridge) and methods for performing a biochemical assay using the microfluidics device to measure an analyte in a sample.
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