METHOD FOR SCREENING COLORECTAL CANCER METASTASIS INHIBITOR
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United States of America Patent
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Sep 14, 2023
app pub date -
Jul 20, 2021
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Jul 20, 2020
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Abstract
The present disclosure relates to a method for screening a colorectal cancer inhibitor and, more specifically, to a method for screening a colorectal cancer inhibitor wherein a material increasing a binding level of ICAM-1 to SRC is selected as a therapeutic material. In the present disclosure, ICAM-1 is identified to regulate cancer metastasis and angiogenesis in an SRC-dependent manner, thereby exhibiting that ICAM-1 can be a potential target factor for developing a colorectal cancer therapeutic agent. Accordingly, a colorectal cancer therapeutic agent employing the target factor screened by the method of the present disclosure can increase the therapeutic effect for colorectal cancer patients.
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