LARGE SCALE SYNTHESIS OF PHARMACEUTICAL AND BIOLOGIC FORMULATIONS USING THIN FILM FREEZING
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United States of America Patent
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Issued Date -
Sep 14, 2023
app pub date -
Mar 13, 2023
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Mar 13, 2023
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Abstract
The invention encompasses methods for the large-scale (preferably under cGMP or cGLP standards) preparation of micron-sized or submicron-sized particles including pharmaceutical or biologic active agents. The systems and methods include a cryogenic cooling system including a novel shroud that enhances the cooling effects thereby reducing product loss and increasing product yields.
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