COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING RADIATION-INDUCED BYSTANDER EFFECTS CAUSED BY RADIATION OR RADIOTHERAPY

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United States of America Patent

APP PUB NO 20230233517A1
SERIAL NO

17852475

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Abstract

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The invention provides novel compositions and methods for the treatment of Radiation-Induced Bystander Effects (RIBE), resulting from radiation exposure. In one preferred embodiment the inventions includes novel therapeutic agents, including but not limited to quercetin and quercetin analogs, as well as E64, CA074, CA074Me, that interfere with the activity of Cathepsin B.

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THE REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE1800 GRANT STREET 8TH FLOOR DENVER CO 80203

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Jeng-Ting Taoyuan, TW 2 0
Li, Hanzeng Louisville, US 2 0
Liang, Qian Beijing, CN 27 95
Peng, Yu Bejing, CN 71 237
Xue, Ding Louisville, US 14 3
Yu, Jau-Song Taoyuan, TW 18 27
Zhang, Man Beijing, CN 45 65
Zheng, Lingjun Boulder, US 2 0

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