COMPOUNDS AND METHODS FOR BLOCKING APOPTOSIS AND INDUCING AUTOPHAGY

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United States of America Patent

APP PUB NO 20230219898A1
SERIAL NO

18010642

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed herein are small molecules that inhibit apoptosis and promote autophagy through the TRADD pathway, and their use for treatment of neurodegenerative diseases. Methods of preparing these small molecules and medicinal efficacy are described.

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Patent Owner(s)

Patent OwnerAddress
HARVARD COLLEGE17 QUINCY STREET CAMBRIDGE MA 02138 02138

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cuny, Gregory D Houston, US 85 957
Jin, Mingzhi Shanghai, CN 3 0
Xu, Daichao Brookline, US 1 0
Yuan, Junying Waban, US 55 499
Zhao, Heng Dedham, US 31 114
Zhu, Hong San Diego, US 257 1272

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