COMPOSITIONS AND METHODS FOR PREVENTION OF CORONAVIRUS INFECTION
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United States of America Patent
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Jul 13, 2023
app pub date -
May 18, 2021
filing date -
May 18, 2020
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Abstract
The present invention relates to griffithsin polypeptides and methods of using the same in inhibition of viral infection. Certain embodiments of the present invention relate to modified griffithsin polypeptides and methods of inhibiting coronavirus infection in a host by administering modified griffithsin polypeptides to the upper respiratory tract of the host. Further embodiments relate to an intranasal spray formulation including griffithsin polypeptides in a composition including a preservative and a viscosity modifier.
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