METHOD AND COMPOSITION FOR MICROBIOME BASED AMELIORATION OF SKIN ASSOCIATED AUTOIMMUNE INFLAMMATORY DISEASES
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United States of America Patent
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Issued Date -
Jul 13, 2023
app pub date -
Jan 29, 2021
filing date -
Jan 29, 2020
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Abstract
Skin-associated autoimmune diseases are common these days. A method and composition for microbiome based amelioration of skin associated autoimmune inflammatory diseases has been provided. The composition is made of at least one or more of microbiome-associated compounds such as proteins, metabolites, antibiotics, probiotics, etc. The method provides a composition for an affected individual through application of these compositions aimed at improving the bioavailability of lipoic acid. It acts through modulation of the lipoic acid metabolic pathway to do the same. The suggested microbes and compounds can either be used as an effective probiotic supplement in increasing the microbial population involved in lipoic acid biosynthesis (only), or increasing the number of competitors of the microbes involved in escalation of lipoic acid salvage system, or through direct antibiotic or physical action against the latter.
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