A METHOD OF DECREASING CONCENTRATION OF TAU (T) PROTEIN AND/OR PHOSPHORYLATED TAU (T) PROTEIN

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United States of America Patent

APP PUB NO 20230212250A1
SERIAL NO

17609731

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Abstract

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This disclosure relates to a method of decreasing concentration of tau (τ) protein and/or phosphorylated tau (τ) protein in a target cell of a human or animal subject having Alzheimer's Disease (AD). The disclosure extends to use of biopharmaceutical agents including (i). 37 kDa/67 kDa laminin receptor precursor/high affinity laminin receptor (LRP/LR) and/or a fragment thereof, or (ii). a transfecting agent for the expression of LRP/LR, for use in treating Alzheimer's Disease (AD).

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF THE WITWATERSRAND JOHANNESBURG1 JAN SMUTS AVENUE JOHANNESBURG GAUTENG 2001

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BIGNOUX, Monique J Johannesburg, ZA 1 0
CUTTLER, Katelyn Johannesburg, ZA 2 0
OTGAAR, Tyrone Chad Johannesburg, ZA 4 0
VAN, DER MERWE Eloise Johannesburg, ZA 3 0
WEISS, Stefan Franz Thomas Johannesburg, ZA 8 0

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