INFLUENZA VIRUS PRODUCTION METHOD USING SINGLE-USE CULTURE PROCESS SYSTEM AND RAPID CONFIRMATION TEST OF INFLUENZA VIRUS ANTIGEN PURIFICATION CONDITION

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United States of America Patent

APP PUB NO 20230212230A1
SERIAL NO

17922262

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Abstract

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The present invention relates to an influenza virus production method using a disposable culture process system, and a test for quickly checking conditions for influenza virus antigen purification. According to the present invention, conditions for influenza surface antigen obtainment (purification) may be quickly and reliably checked according to the unique method of the present invention, even without using the single radial immunodiffusion technique which is conventionally used as a standard test method when producing influenza vaccines, and thus the production time for an influenza surface antigen subunit vaccine is notably reduced, thereby enabling quick response as a result of rapid vaccine development/manufacturing, even in a rapid novel influenza pandemic situation. In addition, according to the influenza virus production method of the present invention, culture media exchange may be carried out in an airtight system by using a continuous low-speed centrifuge using a disposable bag, and thus the possibility of contamination occurring during the virus production process may be greatly reduced.

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SK BIOSCIENCE CO LTD310 PANGYO-RO BUDANG-GU SEONGNAM-SI GYEONGGI-DO 13494

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
JUNG, Hwan-ui Gyeonggi-do, KR 1 0
KIM, Hun Gyeonggi-do, KR 120 572
KIM, Yun-hee Gyeonggi-do, KR 75 907
PARK, Yong Wook Gyeonggi-do, KR 14 58

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges8738788201 - 1011 - 200500100015002000250030003500400045005000550060006500700075008000850090009500

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