METHOD OF MANUFACTURING MICRODEVICES FOR LAB-ON-CHIP APPLICATIONS

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United States of America Patent

APP PUB NO 20230203448A1
SERIAL NO

18009231

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Abstract

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A method of manufacturing a microstructure comprises printing a positive mold structure, filling the positive mold structure with a second material to form an elastically deformable negative mold structure, filling the negative mold structure with a third material to form the microstructure, and releasing the microstructure from the negative mold structure. Advantageously, the negative mold structure can be stretched to facilitate the release of the microstructure. For example, the microstructure comprises a chamber with capped micropillars for the generation and/or analysis of muscle tissue.

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Patent Owner(s)

Patent OwnerAddress
ACADEMISCH ZIEKENHUIS LEIDEN H O D N LUMCALBINUSDREEF 2 LEIDEN 2333 ZA
ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAMDR MOLEWATERPLEIN 50 ROTTERDAM 3015 GE
WAGENINGEN UNIVERSITEITDROEVENDAALSESTEEG 4 WAGENINGEN 6708 PB

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
DE, GREEF Jessica Christine Leiden, NL 1 1
IULIANO, Alessandro Rotterdam, NL 1 1
PIJNAPPEL, Wilhelmus Wenceslaus Matthias Vleuten, NL 12 11
SAGGIOMO, Vittorio Wageningen, NL 2 1
VAN, DER MAAREL Silvere Maria Oegstgeest, NL 3 2
VAN, DER PLOEG Antje Tjitske Poortugaal, NL 11 10
VAN, DER WAL Erik The Hague, NL 11 10

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