MODULAR DRUG PRODUCTION SYSTEM
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United States of America Patent
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Issued Date -
Jun 29, 2023
app pub date -
Dec 20, 2022
filing date -
Dec 23, 2021
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Abstract
A portable system for producing a formulation comprising lipid nanoparticle (LNP)-encapsulated RNA includes: a first sub-system comprising multiple drug substance formulation modules, the first sub-system comprising: a transcription module for forming an RNA solution via in vitro transcription; and a second sub-system operatively downstream of the first sub-system comprising multiple drug product formation modules, the second sub-system comprising: an LNP formulation module for producing a first RNA-LNP preparation from the RNA solution, wherein each of the transcription module and the LNP formulation module is contained within a separate standard shipping container.
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