METHODS OF TREATING ABNORMAL CELL GROWTH
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United States of America Patent
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Jun 29, 2023
app pub date -
Apr 27, 2021
filing date -
Apr 27, 2020
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Abstract
The present invention relates to methods for treating abnormal cell growth (e.g., cancer) in a subject identified as having a KRAS mutation (e.g., KRAS G12X mutation (e.g., KRAS G12V, KRAS G12D, KRAS G12A, KRAS G12R, KRAS G12S, or KRAS G12C)) comprising administering to the subject an effective amount of a MEK inhibitor (e.g., a dual RAF/MEK inhibitor) alone or in combination with an additional agent.
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