COMPOSITIONS AND METHODS FOR TREATING LEUKEMIA
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United States of America Patent
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Issued Date -
Jun 29, 2023
app pub date -
Apr 19, 2021
filing date -
Apr 17, 2020
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Abstract
Compositions and methods for treating leukemia are provided herein. One embodiment provides a method of treating leukemia in a subject in need thereof by administering to a subject in need thereof a composition that selectively inhibits Akt3 by an amount effective to reduce the immune suppressive response in the subject. In one embodiment, the Akt3 inhibitors include, but are not limited to, compounds 1-31 and Formulas I-III.
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