CARRIER-PROTEIN POLYSACCHARIDE CONJUGATION METHODS

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United States of America Patent

APP PUB NO 20230183147A1
SERIAL NO

18171055

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure provides methods of preparing heteroaryl-containing compounds, wherein an azide-alkyne cycloaddition is accelerated in the presence of lauryldimethylamine oxide (LDAO). The present disclosure further provides conjugates of polypeptides and antigens prepared using such methods.

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Patent Owner(s)

Patent OwnerAddress
VAXCYTE INC825 INDUSTRIAL ROAD SUITE 300 SAN CARLOS CA 94070

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
FAIRMAN, Jeffery C Mountain View, US 5 8
KAPOOR, Neeraj Foster City, US 15 297
PILL, Lucy Estella Burlingame, US 1 0
SNYDER, Scott Union City, US 24 383

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