ADJUVANTED CONJUGATE OPIOID VACCINE
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United States of America Patent
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Issued Date -
Jun 15, 2023
app pub date -
May 25, 2021
filing date -
May 27, 2020
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Abstract
The adjuvanted conjugate opioid vaccine described herein is a conjugate of a protein carrier and at least one opioid backbone component or hapten conjugated thereto, admixed with at least one adjuvant. Anti-opioid effects are demonstrated after administration of a vaccine made up of the CRM197 protein carrier linked to a FEN backbone, combined with adjuvants such as dmLT or LTA1.
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