ENHANCED CHARACTERIZATION OF BREAST CANCER
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United States of America Patent
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Jun 8, 2023
app pub date -
Dec 7, 2022
filing date -
Dec 7, 2021
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Provided herein a method for enhanced assessment of breast cancer in a subject including identification of circulating breast cancer cells in a biological sample and single-cell, whole-genome sequencing of the identified circulating breast cancer cells. Optionally, cell-free tumor DNA is further assessed from the same biological sample or a parallel sample. Also provided are methods of treating a subject with breast cancer using the enhanced assessment to select one or more anti-cancer agents for administering to the subject.
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