METHODS OF MAKING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS

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United States of America Patent

APP PUB NO 20230174933A1
SERIAL NO

17801665

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Abstract

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This disclosure provides methods of making immune effector cells (for example, T cells, NK cells) that comprise (i) a nucleic acid molecule that encodes a controllable chimeric antigen receptor (CCAR) or (ii) a nucleic acid molecule that encodes a CAR and a regulatory molecule, and compositions generated by such methods.

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Patent Owner(s)

Patent OwnerAddress
NOVARTIS AGLICHTSTRASSE 35 BASEL 4056

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BONDANZA, Attilio Basel, CH 15 48
BROGDON, Jennifer Sudbury, US 56 1954
CARBONNEAU, Seth Roxbury, US 4 26
DRANOFF, Glenn Sudbury, US 74 1078
ENGELS, Boris Arlington, US 27 545
Greene, Michael R Groton, US 9 74
GUIMARAES, Carla Patricia Pinto Boston, US 7 73
HACK, Anniesha East Hanover, US 4 24
HILD, Marc Horst Peter Wellesley, US 5 28
KODRASI, Olja Quincy, US 4 24
LIM, Hyungwook Cambridge, US 8 26
PRATICO, Elizabeth Dorothy East Boston, US 4 24
PRICE, Andrew Cambridge, US 58 2485
SHARMA, Sujata Ashland, US 6 171
SOHONI, Akash Cambridge, US 4 24
STEIN, Andrew Marc Cambridge, US 8 38
TREANOR, Louise Cambridge, US 4 24
ZHU, Xu Cambridge, US 46 993

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